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ISRgn1, an insertion sequence of the IS3 family, has been identified in the genome of a bacteriocin-negative mutant of Ruminococcus gnavus E1. The copy number of ISRgn1 in R. gnavus E1, as well as its distribution among phylogenetically E1-related strains, has been determined. Results obtained suggest that ISRgn1 is not indigenous to the R. gnavus phylogenetic group but that it can transpose in this bacterium.

applied and environmental microbiology

Characterization of ISRgn 1 , a Novel Insertion Sequence of the IS 3 Family Isolated from a Bacteriocin-Negative Mutant of Ruminococcus gnavus E1