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E. coli ’s ability to survive in, grow in, and colonize the gastrointestinal tract stems from its use of partially digested food and hydrolyzed glycosylated proteins (mucins) from the intestinal mucus layer as substrates. These includel -fucose andl -rhamnose, two 6-deoxyhexose sugars, whose catabolic pathways have been established by genetic and biochemical studies.

Functional Analysis of Deoxyhexose Sugar Utilization in Escherichia coli Reveals Fermentative Metabolism under Aerobic Conditions