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Using the NCCLS agar dilution method, we studied the in vitro activity of retapamulin (SB-275833) against 141 clinical isolates of Propionibacterium species, including seven multiresistant strains, and found retapamulin to be the most active agent among those tested with MICs of &lt; or = 1 microg/ml against all isolates.

antimicrobial agents and chemotherapy

Comparative In Vitro Activities of Retapamulin (SB-275833) against 141 Clinical Isolates of <i>Propionibacterium</i> spp., Including 117 <i>P. acnes</i> Isolates

Comparative In Vitro Activities of Retapamulin (SB-275833) against 141 Clinical Isolates of Propionibacterium spp., Including 117 P. acnes Isolates