Open AccessNonconjugative Transposition of the vanB -Containing Tn 5382 -Like Element in Enterococcus faecium
Author(s) -
Kristin Hegstad,
Torunn P. Røkenes,
Eirik W. Lundblad,
Arnfinn Sundsfjord
Publication year - 2003
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.47.2.786-789.2003
Subject(s) - transposition (logic) , enterococcus faecium , transposable element , operon , microbiology and biotechnology , plasmid , biology , glycopeptide , ampicillin , insertion sequence , amp resistance , genetics , enterococcus , antibiotics , escherichia coli , dna , gene , philosophy , genome , linguistics
The vanB2 operon encoding glycopeptide resistance is an integral part of the putative conjugative transposon Tn5382. Characterization of clinical glycopeptide resistant derivatives from an epidemic ampicillin-resistant Enterococcus faecium strain showed precise chromosomal or plasmid insertions of a vanB2-containing Tn5382-like element. Conjugative transposition of the Tn5382-like element was not demonstrated in retransfer studies.
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