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The activities of telithromycin and levofloxacin against 99 mycoplasma strains were compared to those of several macrolides, ofloxacin, and doxycycline. Telithromycin MICs of ≤0.25 μg/ml were found for all isolates, except forMycoplasma hominis , while levofloxacin was active at concentrations of ≤1 μg/ml against all species studied.

Comparative Activities of Telithromycin (HMR 3647), Levofloxacin, and Other Antimicrobial Agents against Human Mycoplasmas