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A plasmid-encoded extended-spectrum TEM β-lactamase with a pI of 5.5 was detected in aCapnocytophaga ochracea clinical isolate. Thebla gene was associated with a strong TEM-2 promoter and was derived frombla TEM-1a with a single-amino-acid substitution: Glu104 →Lys, previously assigned to TEM-17, which is thus the first TEM β-lactamase to be reported in the phylumFlavobacter-Bacteroides .

antimicrobial agents and chemotherapy

<i>Capnocytophaga ochracea</i> : Characterization of a Plasmid-Encoded Extended-Spectrum TEM-17 β-Lactamase in the Phylum <i>Flavobacter-Bacteroides</i>

Capnocytophaga ochracea : Characterization of a Plasmid-Encoded Extended-Spectrum TEM-17 β-Lactamase in the Phylum Flavobacter-Bacteroides