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Studies were made of the synthesis of beta-galactosidase by Escherichia coli in the presence of 5-fluorouracil, streptomycin, and subinhibitory concentrations of chloramphenicol. The preferential inhibition of beta-galactosidase synthesis observed in the presence of the above drugs was found to be caused by catabolite repression.

Catabolite Repression in Inhibition of β-Galactosidase Synthesis by Escherichia coli in the Presence of Agents Producing Translation Errors