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Clinical studies have suggested thatbla OXA-40 -positiveAcinetobacter baumannii isolates are associated with poor patient outcomes; however, reasons for unfavorable outcomes are difficult to discern in clinical studies. The objective of this study was to assess the virulence of carbapenem-resistantA. baumannii according tobla OXA-40 and epidemiological outbreak status in aGalleria mellonella model. Eight isolates ofA. baumannii were studied. Nonoutbreak isolates andbla OXA-40 -negative isolates more rapidly killed infectedG. mellonella (P &lt; 0.01).

antimicrobial agents and chemotherapy

Pathogenicity of Clinical Acinetobacter baumannii Isolates in a Galleria mellonella Host Model According to <i>bla</i> <sub>OXA-40</sub> Gene and Epidemiological Outbreak Status

Pathogenicity of Clinical Acinetobacter baumannii Isolates in a Galleria mellonella Host Model According to bla OXA-40 Gene and Epidemiological Outbreak Status

Pathogenicity of Clinical Acinetobacter baumannii Isolates in a Galleria mellonella Host Model According to bla _OXA-40 Gene and Epidemiological Outbreak Status