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Adults with cystic fibrosis (CF) frequently harborStaphylococcus aureus , which is increasingly antibiotic resistant. Telavancin is a once-daily rapidly bactericidal antibiotic active against methicillin-, linezolid-, and ceftaroline-resistantS. aureus . Because CF patients experience alterations in pharmacokinetics, the optimal dose of telavancin in this population is unknown.

Pharmacokinetics of Telavancin in Adult Patients with Cystic Fibrosis during Acute Pulmonary Exacerbation