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Pep5 (WELVVLGKL) is a fragment of cyclin D2 that exhibits a 2-fold increase in the S phase of the HeLa cell cycle. When covalently bound to a cell-penetrating peptide (Pep5-cpp), the nonapeptide induces cell death in several tumor cells, including breast cancer and melanoma cells.

antimicrobial agents and chemotherapy

Pep5, a Fragment of Cyclin D2, Shows Antiparasitic Effects in Different Stages of the <i>Trypanosoma cruzi</i> Life Cycle and Blocks Parasite Infectivity

Pep5, a Fragment of Cyclin D2, Shows Antiparasitic Effects in Different Stages of the Trypanosoma cruzi Life Cycle and Blocks Parasite Infectivity