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A divergently oriented ampR has been located upstream of blaL2 in Stenotrophomonas maltophilia. AmpR is necessary for L1 and L2 beta-lactamase induction in response to beta-lactam challenge, and activation of AmpR is sufficient to induce L1 and L2 production. L1 induction requires more activation of AmpR than does L2 induction.

Induction of L1 and L2 β-Lactamase Production inStenotrophomonas maltophiliaIs Dependent on an AmpR-Type Regulator