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Transferable quinolone resistance has not previously been reported in Argentina. Here we describe three complex class 1 integrons harboring the novel allele qnrB10 in a unique region downstream of orf513, one of them also containing aac(6')-Ib-cr within the variable region of integrons. The three arrays differed from bla(CTX-M-2)-bearing integrons, which are broadly distributed in Argentina.

antimicrobial agents and chemotherapy

Complex Class 1 Integrons with Diverse Variable Regions, Including aac ( 6 ′)- Ib - cr , and a Novel Allele, qnrB10 , Associated with IS CR1 in Clinical Enterobacterial Isolates from Argentina