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The genetic elements carrying macrolide resistance genes in Streptococcus pneumoniae isolates belonging to CC271 were investigated. The international clone Taiwan(19F)-14 was found to carry Tn2009, a Tn916-like transposon containing tet(M) and mef(E). The dual erm(B) mef(E) isolates carried Tn2010, which is similar to Tn2009 with the addition of a putative new transposon, the erm(B) genetic element.

antimicrobial agents and chemotherapy

The Macrolide Resistance Genes erm (B) and mef (E) Are Carried by Tn 2010 in Dual-Gene Streptococcus pneumoniae Isolates Belonging to Clonal Complex CC271