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Colistin appears more and more frequently as a last-line defense therapy against nosocomial infections due to multiresistant Gram-negative bacteria ([8][1]). For parenteral administration, colistin is used as a prodrug, colistin methanesulfonate (CMS), which is less toxic but inactive and hydrolyzed

Colistin Distribution in the Peritoneal Fluid of a Patient with Severe Peritonitis