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Among a collection of 48 multidrug-resistant pneumococcal strains colonizing healthy children in a small municipality of Mérida, Venezuela, we identified sequence types (STs) related to a variety of internationally spreading drug-resistant clones, as well as ST135, thus far isolated only in Europe. The clones invariably harbored one or more of the Tn916-related transposons Tn3872, Tn5253, Tn6002, Tn2009, and Tn2010. Finally, our data suggest both structural rearrangements in certain transposons and occurrence of novel transposable elements.

antimicrobial agents and chemotherapy

Genetic Diversity of Tn <i>916</i> -Related Transposons among Drug-Resistant Streptococcus pneumoniae Isolates Colonizing Healthy Children in Venezuela

Genetic Diversity of Tn 916 -Related Transposons among Drug-Resistant Streptococcus pneumoniae Isolates Colonizing Healthy Children in Venezuela