Open AccessIn Vitro Activities of Bedaquiline and Delamanid against Nontuberculous Mycobacteria Isolated in Beijing, China
Author(s) -
Xia Yu,
Xiaopan Gao,
Chenghai Li,
Jingjing Luo,
Shu’an Wen,
Tingting Zhang,
Yifeng Ma,
Lingling Dong,
Fen Wang,
Hairong Huang
Publication year - 2019
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.00031-19
Subject(s) - bedaquiline , nontuberculous mycobacteria , microbiology and biotechnology , biology , mycobacterium fortuitum , antibiotics , mycobacterium kansasii , mycobacterium , medicine , bacteria , tuberculosis , mycobacterium tuberculosis , pathology , genetics
Due to the natural resistance of nontuberculous mycobacteria (NTM) against multiple antibiotics, treatment of infections caused by them is often long-course and less successful. The main objective of our study was the evaluation ofin vitro susceptibility of 209 isolates consisting of different NTM species against bedaquiline and delamanid. Furthermore, reference strains of 33 rapidly growing mycobacterium (RGM) species and 19 slowly growing mycobacterium (SGM) species were also tested.
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