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Serum Immunoglobulin G Antibody Responses to Bordetella pertussis Lipooligosaccharide and B. parapertussis Lipopolysaccharide in Children with Pertussis and Parapertussis
Author(s) -
Birger Trollfors,
Teresa Lagergård,
J Taranger,
Elisabet Bergfors,
Rachel Schneerson,
John B. Robbins
Publication year - 2001
Publication title -
clinical and diagnostic laboratory immunology
Language(s) - English
Resource type - Journals
eISSN - 1098-6588
pISSN - 1071-412X
DOI - 10.1128/cdli.8.5.1015-1017.2001
Subject(s) - bordetella pertussis , lipopolysaccharide , antibody , immunoglobulin g , microbiology and biotechnology , immunology , whooping cough , pertussis toxin , biology , medicine , g protein , vaccination , bacteria , receptor , genetics
Serum immunoglobulin G (IgG) antibodies against the lipooligosaccharide (LOS) of Bordetella pertussis and the lipopolysaccharide (LPS) of Bordetella parapertussis were measured by enzyme-linked immunosorbent assay in paired sera from 40 children with pertussis and 14 with parapertussis. Wide differences in the individual responses were noted. Both anti-LOS and -LPS IgG levels increased significantly in the children with pertussis, as did anti-LPS but not anti-LOS in those with parapertussis.

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