Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice | Zendy

Yusuke Shono | Zendy; Melissa D. Docampo | Zendy; Jonathan U. Peled | Zendy; Suelen Martins Perobelli | Zendy; Enrico Velardi | Zendy; Jennifer J. Tsai | Zendy; Ann E. Slingerland | Zendy; Odette M. Smith | Zendy; Lauren Young | Zendy; Jyotsna Gupta | Zendy; Sophia R. Lieberman | Zendy; Hillary Jay | Zendy; Katya Ahr | Zendy; Kori A. Porosnicu Rodriguez | Zendy; Ke Xu | Zendy; Marco Calarfiore | Zendy; Hendrik Poeck | Zendy; Silvia Caballero | Zendy; Sean M. Devlin | Zendy; Franck Rapaport | Zendy; Jarrod A. Dudakov | Zendy; Alan M. Hanash | Zendy; Boglarka Gyurkocza | Zendy; Gëorge F. Murphy | Zendy; Camilla Borges Ferreira Gomes | Zendy; Chen Liu | Zendy; Eli L. Moss | Zendy; Shan B. Falconer | Zendy; Ami S. Bhatt | Zendy; Ying Taur | Zendy; Eric G. Pamer | Zendy; Marcel R.M. van den Brink | Zendy; Robert R. Jenq | Zendy

Open Access

Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice

Author(s) -

Yusuke Shono,

Melissa D. Docampo,

Jonathan U. Peled,

Suelen Martins Perobelli,

Enrico Velardi,

Jennifer J. Tsai,

Ann E. Slingerland,

Odette M. Smith,

Lauren Young,

Jyotsna Gupta,

Sophia R. Lieberman,

Hillary Jay,

Katya Ahr,

Kori A. Porosnicu Rodriguez,

Ke Xu,

Marco Calarfiore,

Hendrik Poeck,

Silvia Caballero,

Sean M. Devlin,

Franck Rapaport,

Jarrod A. Dudakov,

Alan M. Hanash,

Boglarka Gyurkocza,

Gëorge F. Murphy,

Camilla Borges Ferreira Gomes,

Chen Liu,

Eli L. Moss,

Shan B. Falconer,

Ami S. Bhatt,

Ying Taur,

Eric G. Pamer,

Marcel R.M. van den Brink,

Robert R. Jenq

Publication year - 2016

Publication title -

science translational medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.819

H-Index - 216

eISSN - 1946-6242

pISSN - 1946-6234

DOI - 10.1126/scitranslmed.aaf2311

Subject(s) - hematopoietic stem cell transplantation , broad spectrum , stem cell , antibiotics , haematopoiesis , medicine , transplantation , immunology , graft versus host disease , disease , hematopoietic stem cell , neutropenia , hematopoietic cell , biology , chemotherapy , microbiology and biotechnology , chemistry , combinatorial chemistry , genetics

Treating neutropenic fever with broad-spectrum antibiotics after allogeneic hematopoietic stem cell transplant is associated with an increase in graft-versus-host disease in mice and humans.

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