Open AccessMG53-mediated cell membrane repair protects against acute kidney injury
Author(s) -
Pu Duann,
Haichang Li,
PeiHui Lin,
Tao Tan,
Zhen Wang,
Ken Chen,
Xinyu Zhou,
Kristyn Gumpper,
Hua Zhu,
Thomas Ludwig,
Peter J. Mohler,
Brad H. Rovin,
William T. Abraham,
Chunyu Zeng,
Jianjie Ma
Publication year - 2015
Publication title -
science translational medicine
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 6.819
H-Index - 216
eISSN - 1946-6242
pISSN - 1946-6234
DOI - 10.1126/scitranslmed.3010755
Subject(s) - acute kidney injury , kidney , proximal tubule , medicine , ischemia , recombinant dna , pharmacology , microbiology and biotechnology , chemistry , biology , biochemistry , gene
Recombinant MG53 translocates to sites of injury in the proximal tubule of the kidney and protects mice from acute kidney injury induced by ischemia or drugs.
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