Open AccessSynthetic Genome Brings New Life to Bacterium
Author(s) -
Elizabeth Pennisi
Publication year - 2010
Publication title -
science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 12.556
H-Index - 1186
eISSN - 1095-9203
pISSN - 0036-8075
DOI - 10.1126/science.328.5981.958
Subject(s) - genome , bacteria , synthetic biology , biology , circular bacterial chromosome , dna , computational biology , bacterial genome size , chromosome , genetics , gene
In this week'sScience Express, researchersdescribe the stepwise creation of a bacterial chromosome and the successful transfer of it into a bacterium, where it replaced the native DNA. Powered by the synthetic genome, that microbial cell began replicating and making a new set of proteins.
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