Open AccessMinimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants
Author(s) -
Helena de Puig,
Rose Lee,
Devora Najjar,
Xiao Tan,
Luis R. Soekensen,
Nicolaas M. Angenent-Mari,
Nina M. Donghia,
Nicole E. Weckman,
Audrey Ory,
Carlos F. Ng,
Peter Q. Nguyen,
Angelo S. Mao,
Thomas Ferrante,
Geoffrey Lansberry,
Hani Sallum,
James B. Niemi,
James J. Collins
Publication year - 2021
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abh2944
Subject(s) - crispr , covid-19 , point of care , computational biology , point of care testing , medicine , virology , biology , bioinformatics , intensive care medicine , genetics , pathology , infectious disease (medical specialty) , disease , gene , outbreak
An integrated, low-cost, sample-to-answer, CRISPR-based diagnostic detects SARS-CoV-2 and variants from unprocessed saliva.