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ability of action potential induction falls off exponentially with dis-tance. Somata and primary apical dendrites are most sensitive to un-Journal of Biomedical Optics 10(1), 011003 (January/February 2005)Dusseldorf, Germany caged glutamate with locally increased sensitivity on proximal apical dendrites. We conclude that optical stimulation can be targeted with high precision. © 2005 Society of Photo-Optical Instrumentation Engineers. [DOI: 10.1117/1.1852555

Optical release of caged glutamate for stimulation of neurons in the in vitro slice preparation