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In this paper, we study bilogical polymeric molecular nanostructures, focusing on ribonucleic acids (RNA) and their behaviour in fluids, in particular in physiological solutions. First, we give a brief overview of the most recent results in this field related to the properties of these structures that can be characterised by root mean square deviation, radius of gyration and radial distribution function. Among other things, we provide insight into typical distributions of 23Na+and 35Cl−ions around the RNA nanotubes as a function of time within a distance of 5 Å from their surface. Finally, we provide details of the recent achievements in the coarse grain modeling of the such bilogical nanotubes.

Modelling Biological Polymeric Nanostructures in Physiological Fluids: Focus on Ribonucleic Acid Nanotubes