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During the fifteen-year period between 1985 and 1999, a total of 1,985 strains of Group B Streptococci isolated in Sapporo City General Hospital were classified by agglutination method. The results were summarized as follows: 1. Type distribution of 1,513 isolates of group B streptococci in and after 1992 when type NT6 and type JM9 were started to be typed for the first time was as follows; according to rate isolation it was in the order of type NT6 (412 strains 27.3%), JM9 (257 17.0%), III (220 14.5%), Ia (182 12.0%), following IV, Ib, V and II. 2. As for proportion of origin-materials of isolates, vaginal discharge was 49.5%, urine 26.8%, throat swab 6.8%, sputum 6.6%, pus or exudate 4.2%, blood or spinal fluid 1.8% and stomach contents was 1.3%. A proportion of vagina-origin strains went up to 55% in the second half (1992-1999) from 23% in the first half (1985-1991). 3. In type distribution of isolates in terms of origin-materials, the proportion of type III was significant by high in the stomach contents and blood and spinal fluid. Proportion of type Ia was significant by high in the sputum or throat swab. 4. Thirteen out of 28 strains (46.4%) from newborns were type III; 3 out of 4 (75.0%) from spinal fluid, 5 out of 10 (50.0%) from blood, 5 out of 13 (35.7%) from stomach contents.

Long-Term Obsevations on Type Distribution of Clinical Isolates of ^|^beta;-Hemolytic Streptococci in Sapporo