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Studies of psychological factors in ulcerative colitis (UC) have produced inconsistent findings. This study sought to determine whether perinuclear antineutrophil cytoplasmic antibody (pANCA) demarcates subtypes which differ with respect to psychobiological interactions.

Psychobiological Subtypes of Ulcerative Colitis: pANCA Status Moderates the Relationship Between Disease Activity and Psychological Distress