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We present in vitro sensing of glucose using a newly developed efficient optical fiber glucose sensor based on a compound parabolic concentrator (CPC)-tipped polymer optical fiber (POF). A batch of nine CPC-tipped POF sensors with a 35-mm fiber length is shown to have an enhanced fluorescence pickup efficiency with an average increment factor of 1.7 as compared with standard POF sensors with a plane cut fiber tip. in vitro measurements for two glucose concentrations (40 and 400 mg/dL) confirm that the CPC-tipped sensors can efficiently detect both glucose concentrations.

Polymer Optical Fiber Compound Parabolic Concentrator Fiber Tip-Based Glucose Sensor: In Vitro Testing