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Diagnosis is a critical preventive step in Coronavirus research which has similar manifestations with other types of pneumonia. CT scans and X-rays play an important role in that direction. However, processing chest CT images and using them to accurately diagnose COVID-19 is a computationally expensive task. Machine Learning techniques have the potential to overcome this challenge. This article proposes two optimization algorithms for feature selection and classification of COVID-19. The proposed framework has three cascaded phases. Firstly, the features are extracted from the CT scans using a Convolutional Neural Network (CNN) named AlexNet. Secondly, a proposed features selection algorithm, Guided Whale Optimization Algorithm (Guided WOA) based on Stochastic Fractal Search (SFS), is then applied followed by balancing the selected features. Finally, a proposed voting classifier, Guided WOA based on Particle Swarm Optimization (PSO), aggregates different classifiers&#x2019; predictions to choose the most voted class. This increases the chance that individual classifiers, e.g. Support Vector Machine (SVM), Neural Networks (NN), k-Nearest Neighbor (KNN), and Decision Trees (DT), to show significant discrepancies. Two datasets are used to test the proposed model: CT images containing clinical findings of positive COVID-19 and CT images negative COVID-19. The proposed feature selection algorithm (SFS-Guided WOA) is compared with other optimization algorithms widely used in recent literature to validate its efficiency. The proposed voting classifier (PSO-Guided-WOA) achieved AUC (area under the curve) of 0.995 that is superior to other voting classifiers in terms of performance metrics. Wilcoxon rank-sum, ANOVA, and T-test statistical tests are applied to statistically assess the quality of the proposed algorithms as well.

Novel Feature Selection and Voting Classifier Algorithms for COVID-19 Classification in CT Images