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In the title compound, C26H27N5O, the piperazine ring adopts a chair conformation. The pyrimidine ring makes a dihedral angle of 1.5 (1)° with the meth­oxy­phenyl ring and 33.1 (1)° with the quinoline ring system. In the crystal, mol­ecules are consolidated in the crystal packing by weak C—H⋯π inter­actions and π–π stacking inter­actions.

3-[6-(4-Methoxyphenyl)-2-methylpyrimidin-4-yl]-2-(4-methylpiperazin-1-yl)quinoline