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In the title chalcone derivative, C18H18O5, the dihedral angle formed by the planes of the benzene rings is 29.6 (2)° and an intramolecular O—H...O hydrogen bond closes an S(6) ring. In the crystal, weak C—H...O hydrogen bonds link molecules into chains propagating along [001]

(E)-3-(2,3-Dimethoxyphenyl)-1-(2-hydroxy-5-methoxyphenyl)prop-2-en-1-one