Open AccessStructure of d(CCGGGACCGG) 4 as a four‐way junction at 1.6 Å resolution: new insights into solvent interactions
Author(s) -
Chakraborty Arka,
Mandal Pradeep Kumar,
Gautham Namasivayam
Publication year - 2012
Publication title -
acta crystallographica section f
Language(s) - English
Resource type - Journals
ISSN - 1744-3091
DOI - 10.1107/s1744309112034926
Subject(s) - resolution (logic) , sequence (biology) , crystal structure , solvent , crystallography , high resolution , low resolution , materials science , chemical physics , chemistry , computer science , organic chemistry , geology , artificial intelligence , biochemistry , remote sensing
The crystal structure of the decamer sequence d(CCGGGACCGG) 4 has previously been reported at 2.16 Å resolution as a four‐way junction. Here, the structure of this sequence is reported at the significantly higher resolution of 1.6 Å, which is the highest resolution reported for a four‐way junction. This allowed the unambiguous identification of an extensive hydration network with distinct patterns and solvent‐mediated interactions that shed new light on the role of water in the formation and stabilization of junction structures.