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The title compound, C 16 H 20 N 4 OS 2 , was synthesized by the reaction of 2-benzyl­sulfanyl-5-chloro­acetamido-1,3,4-thia­diazole and piperidine in a 1:2 ratio. The planes of the acetamide and 1,3,4-thia­diazole units are twisted by 10.8 (4)°. The thia­diazole S atom and the acetamide O atom are  syn -oriented due to a hypervalent S⋯O inter­action of 2.628 (4) Å. In the crystal, mol­ecules form centrosymmetric dimers  via  N—H⋯N hydrogen bonds. These dimers are further connected by C—H⋯O inter­actions into (100) layers.

N-(5-Benzylsulfanyl-1,3,4-thiadiazol-2-yl)-2-(piperidin-1-yl)acetamide