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The title compound, C 17 H 20 O 5 , an eremophilane sesquiternoid, was isolated from the roots of  Ligularia lapathifolia . The mol­ecule contains four fused rings of which the six-membered ring  A  adopts a half-chair conformation, the six-membered ring  B  adopts a chair conformation, the five-membered ring  C  is almost planar (r.m.s. deviation = 0.015 Å) and the five-membered ring  D  adopts an envelope conformation with the quaternary C atom as the flap. The methyl and the eth­oxy groups adopt a  syn  conformation and the  A / B  ring junction is  cis -fused. No directional inter­molecular inter­actions could be identified in the crystal.

8β-Ethoxyeremophil-3,7(11)-diene-8α,12;6α,15-diolide