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In the Schiff base mol­ecule of the title compound, C 22 H 20 N 4 O 2 ·C 3 H 7 NO·2H 2 O, the cyclo­hexane ring adopts a chair conformation with the two imine groups linked at the equatorial positions. The two indolin-2-one ring systems make a dihedral angle of 65.63 (5)°. In the crystal, the Schiff base mol­ecules are connected through bifurcated N—H⋯(O,N) hydrogen bonds, forming inversion dimers. The water molecules link the dimers and the dimethylformamide molecules  via  O—H⋯O, O—H⋯N and N—H⋯O hydrogen bonds. Together with C—H⋯π and π–π [centroid–centroid distance = 3.3889 (10) Å] inter­actions a three-dimensional supra­molecular structure is formed.

(3Z,3′E)-3,3′-[Cyclohexane-1,2-diylbis(azanylylidene)]bis(indolin-2-one)N,N-dimethylformamide monosolvate dihydrate