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In the title compound, C 15 H 25 ClN 5 O 4 P, the r.m.s. deviation for the purine ring system is 0.0165 Å. The coordination about the P atom is a distorted tetrahedron [O=P—O angles = 116.70 (6) and 109.87 (6)°]. In the crystal, molecules are linked by N—H⋯O hydrogen bonds, generating a three-dimensional network.

Diisopropyl {[(R)-2-(2-amino-6-chloro-9H-purin-9-yl)-1-methylethoxy]methyl}phosphonate