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The title compound, C 25 H 23 NO, consists of a biphenyl-4-carbonyl unit attached to an exocyclic double bond group at position 2 of an indole unit, which presents methyl groups as substituents at positions 1 and 3. The mol­ecular conformation is  s-cis  with an  E  configuration, supported by weak intra­molecular C—H⋯O contacts involving the methyl groups and the carbonyl function. The rings of the biphenyl group are twisted by 37.13 (5)°. In the crystal, C—H⋯O and C—H⋯π inter­actions link the molecules.

(E)-1-([1,1′-Biphenyl]-4-yl)-2-(1,3,3-trimethylindolin-2-ylidene)ethanone