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The title compound, C 26 H 24 FNO 3 , is a critical inter­mediate of a selective and competitive inhibitor of the enzyme 3-hy­droxy-3-methyl­glutaryl-coenzyme A (HMG–CoA) reductase. Inter­molecular N—H⋯O hydrogen bonding generates a chain along  [give direction]  that is the dominant inter­action in the crystal packing. Inter­molecular C—H⋯O inter­actions are also observed.

rac-2-[2-(4-Fluorophenyl)-2-oxo-1-phenylethyl]-4-methyl-3-oxo-N-phenylpentanamide