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The title compound, C 19 H 20 N 4 O 4 , is a cyclo­nucleoside with a C—N linkage. The furan­ose ring adopts a twist C3′- endo /C2′- exo  (close to  3T2 ) conformation with a pseudorotational phase angle ( P ) of 8.1° and puckering amplitude ( vm ) of 30.6°. The orientation of the pyrimidine ring with respect to the sugar group is  anti . One intra­molecular C—H⋯O hydrogen bond is observed. The packing features an N—H⋯O hydrogen bond.

N6,3′-cyclo-5′-O-Cyanomethylthymidine

N⁶,3′-cyclo-5′-O-Cyanomethylthymidine