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Ipidacrine (2,3,5,6,7,8-hexa­hydro-1 H -cyclo­penta­[ b ]quinolin-9-amine) was reacted with 4-methoxy­phenyl isocyanate to give the title compound, C 28 H 30 N 4 O 4 . An intra­molecular N—H⋯O hydrogen bond results in an essentially planar [r.m.s. deviation from the mean plane is 0.126 (1) Å] conformation for the biuret unit. The central ring of the quinoline unit is twisted by 78.2 (1)° with respect to the biuret mean plane, whereas the two 4-methoxy­benzene rings are twisted out of this plane by 24.3 (1)° and 48.5 (1)°, resulting in an overall propeller-like structure. An inter­molecular N—H⋯N hydrogen bond between the biuret NH atom and the quinoline ring nitro­gen defines the crystal packing.

3-(2,3,5,6,7,8-Hexahydro-1H-cyclopenta[b]quinolin-9-yl)-1,5-bis(4-methoxyphenyl)biuret