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The title compound, C 12 H 19 BrN 4 O, represents the minor component of the two products obtained in a series of transformations involving the Grignard reaction of  tert -butoxy­carbonyl-protected 4-amino­cyclo­hexa­none with MeMgBr, and subsequent inter­action of the obtained amino-substituted cyclo­hexa­nol with 4-chloro-6-methyl­pyrimidin-2-amine followed by bromination with  N -bromo­succinimide. The X-ray structure showed that this product represents a  trans  isomer with respect to the amino and hydr­oxy substituents in the cyclo­hexyl ring; the dihedral angle between the amino­pyrimidine plane and the (noncrystallographic) mirror plane of the substituted cyclo­hexyl fragment is 33.6 (3)°. Only two of the four potentially ‘active’ H atoms participate in inter­molecular N—H⋯O and O—H⋯N hydrogen bonds, linking the mol­ecules into layers parallel to the (10    ) plane.

trans-4-(2-Amino-5-bromo-6-methylpyrimidin-4-ylamino)-1-methylcyclohexanol