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In the crystal structure of the title compound, C 43 H 46 NO 13 ·0.5H 2 O, the mol­ecule assumes a U-shaped conformation, the terminal benzene rings being approximately parallel and partially overlapped with each other. The mol­ecule contains eight alicyclic and heterocyclic rings. The cyclo­hexane rings adopt chair conformations, the other three six-membered carbocyclic rings form a bicyclo­[2.2.2]octane system with a boat conformation for each six-membered ring, the six-membered heterocyclic ring has a chair conformation and both of the five-membered rings have envelope conformations. The solvent water mol­ecule links with the organic mol­ecule  via  classic O—H⋯O and weak C—H⋯O hydrogen bonding in the crystal structure.

(1β,2α,3α,7α,11α,13β)-1,3,7,11-Tetraacetoxy-2,13-bis(benzyloxy)-21-methyl-19,21-secohetisan-19-al hemihydrate