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The title compound, C 20 H 32 N 2 OS, was obtained during the course of our investigation on 2-alkylsulfanyl-6-benzyl-3,4-dihydropyrimidin-4(3 H )-ones (S–DABOs) showing favourable anti-HIV-1 activity. Both cyclo­hexane rings adopt chair conformations. The angle at the methyl­ene C atom linking the pyrimidine and cyclo­hexane ring is 113.7 (3)°, which is in the range considered optimal for maximum activity of non-nucleoside reverse transcriptase inhibitors. Inter­molecular N—H⋯O hydrogen bonds link the mol­ecules into dimers and stabilize the crystal structure of the compound. In addition, an intra­molecular C—H⋯O hydrogen bond is observed.

6-Cyclohexylmethyl-2-cyclohexylsulfanyl-5-isopropylpyrimidin-4(3H)-one