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In the title compound, C 11 H 17 N 3 O 6 ·H 2 O, an important building block of the medicine cefbuperazone sodium, the piperazine ring adopts a screw-boat conformation. Inter­molecular O—H⋯O and intra­molecular N—H⋯O hydrogen bonds are observed. The water mol­ecule participates as both donor and acceptor in this framework.

(2S,3R)-2-[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonylamino]-3-hydroxybutyric acid monohydrate