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In the centrosymmetric title compound, [Ni(C 6 H 4 NO 2 ) 2 (C 22 H 34 N 6 )], the Ni II  ion is bonded to the four secondary N atoms of the macrocyclic ligand in a square-planar fashion and two carboxyl­ate O atoms of the isonicotinate ions in axial positions, resulting in a tetra­gonally distorted octa­hedron. An offset face-to-face π–π stacking inter­action [centroid–centroid distance = 3.674(4) Å] and N—H⋯N and N—H⋯O hydrogen-bonding inter­actions give rise to a one-dimensional supra­molecular structure in the solid state.

trans-(1,8-Dibenzyl-1,3,6,8,10,13-hexaazacyclotetradecane)diisonicotinatonickel(II)