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In the title compound, C(17)H(15)N(5)O(3)S, the plane of the triazolo-thia-diazole system forms dihedral angles of 15.68 and 4.46° with the planes of the pyridine and furan rings, respectively. In the mol-ecule, there is an intra-molecular C-H⋯N inter-action. The crystal structure also contains other inter-molecular inter-actions, such as C-H⋯O hydrogen bonds, π-π stacking (centroid-centroid distances = 3.746 and 3.444 Å), non-bonded S⋯N [3.026 (2) Å] and C-H⋯π inter-actions.

Ethyl 5-[6-(furan-2-yl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazol-3-yl]-2,6-dimethylnicotinate