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4 After the transition, the crystal totally recovers its crystalline state and diffraction power. The symmetry is reduced from space-group I222 to its subgroup P21212 but the effects of this symmetry breaking on the structure are subtle. The decrease of the uni t -ce l l volume by more tha t 15 percents produces more intense and interesting structural r e a r r a n g e m e n t s in the crystal (see figure).

A comparison of hydrated protein models obtained by crystallography, SAXS and other techniques