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Competition within the immune system may degrade immune control of viralinfections. We formalize the evolution that occurs in both HIV-1 and the immunesystem quasispecies. Inclusion of competition in the immune system leads to anovel balance between the immune response and HIV-1, in which the eventualoutcome is HIV-1 escape rather than control. The analytical model reproducesthe three stages of HIV-1 infection. We propose a vaccine regimen that may beable to reduce competition between T cells, potentially eliminating the thirdstage of HIV-1.Comment: 5 pages, 2 figures, to appear in Phys. Rev. Let

Physical Theory of the Competition that Allows HIV to Escape from the Immune System