English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

We obtain, using transfer matrix methods, the distribution function $P(R)$ ofthe end-to-end distance, the loop formation probability and force-extensionrelations in a model for short double-stranded DNA molecules. Accounting forthe appearance of ``bubbles'', localized regions of enhanced flexibilityassociated with the opening of a few base pairs of double-stranded DNA inthermal equilibrium, leads to dramatic changes in $P(R)$ and unusualforce-extension curves. An analytic formula for the loop formation probabilityin the presence of bubbles is proposed. For short {\em heterogeneous} chains,we demonstrate a strong dependence of loop formation probabilities on sequence,as seen in recent experiments.Comment: 10 page

Distribution Functions, Loop Formation Probabilities, and Force-Extension Relations in a Model for Short Double-Stranded DNA Molecules