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We study the global Q^2 dependence of large x F_2 nucleon structure function data, with the aim of providing a perturbative-QCD (pQCD) based, quantitative analysis of parton-hadron duality. As opposed to previous analyses at fixed x, we use a framework in fixed W^2. We uncover a breakdown of the twist expansion which, by affecting the initial evolution of parton distributions, will have consequences for pQCD analyses also at large x and very large Q^2

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Perturbative QCD Analysis of Local Duality in a Fixed<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msup><mml:mi>W</mml:mi><mml:mn>2</mml:mn></mml:msup></mml:math>Framework

Perturbative QCD Analysis of Local Duality in a FixedW2Framework