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We present evidence of $D^0$-$\bar{D^0}$ mixing using a time-dependentamplitude analysis of the decay D0->K+pi-pi0 in a data sample of 384 fb^-1collected with the BaBar detector at the PEP-II e+e- collider at SLAC. AssumingCP conservation, we measure the mixing parameters x'_{Kpipi0} =[2.61^{+0.57}_{-0.68} (stat.) +- 0.39 (syst.)]%, y'_{Kpipi0} = [-0.06^{+0.55}_{-0.64} (stat.) +- 0.34 (syst.)]%. The confidence level for the datato be consistent with the no-mixing hypothesis is 0.1%, including systematicuncertainties. This result is inconsistent with the no-mixing hypothesis with asignificance of 3.2 standard deviations. We find no evidence of CP violation inmixing.

Measurement of D0-D0bar mixing from a time-dependent amplitude analysis of D0 -> K+ pi- pi0 decays