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I point out that the arguments raised by Vilar and Rubi against thework-Hamiltonian connection in free-energy calculations imply, if correct, thefailure of the statistical mechanical expression of the thermodynamicalfree-energy via the logarithm of the partition function.

Comment on "Failure of the work-Hamiltonian connection for free-energy calculations" by Jose M. G. Vilar and J. Miguel Rubi